AIM2 inflammasome surveillance of DNA damage shapes neurodevelopment
AIM2 inflammasome surveillance of DNA damage shapes neurodevelopment
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Neurodevelopment is characterized by rapid rates of neural cell proliferation and differentiation followed by massive cell death in which more than half of all recently generated brain cells are pruned back. Large amounts of DNA damage, cellular debris, and by-products of cellular stress are generated during these neurodevelopmental events, all of...
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Full title
AIM2 inflammasome surveillance of DNA damage shapes neurodevelopment
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7788527
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7788527
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2174-3