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Overexpression of sortilin is associated with 5‐FU resistance and poor prognosis in colorectal cance...

Overexpression of sortilin is associated with 5‐FU resistance and poor prognosis in colorectal cance...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7810928

Overexpression of sortilin is associated with 5‐FU resistance and poor prognosis in colorectal cancer

About this item

Full title

Overexpression of sortilin is associated with 5‐FU resistance and poor prognosis in colorectal cancer

Publisher

England: John Wiley & Sons, Inc

Journal title

Journal of cellular and molecular medicine, 2021-01, Vol.25 (1), p.47-60

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Colorectal cancer (CRC) is the third most common cancer worldwide. Even if 5‐fluorouracil (5‐FU) is used as the first‐line chemotherapeutic drug, responsiveness is only 20‐30%. Acquired resistance to 5‐FU contributes to both poor patient prognosis and relapse, emphasizing the need to identify biomarkers. Sortilin, a vacuolar protein sorting 10 prot...

Alternative Titles

Full title

Overexpression of sortilin is associated with 5‐FU resistance and poor prognosis in colorectal cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7810928

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7810928

Other Identifiers

ISSN

1582-1838

E-ISSN

1582-4934

DOI

10.1111/jcmm.15752

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