Natural cystatin C fragments inhibit GPR15-mediated HIV and SIV infection without interfering with G...
Natural cystatin C fragments inhibit GPR15-mediated HIV and SIV infection without interfering with GPR15L signaling
About this item
Full title
Author / Creator
Hayn, Manuel , Blötz, Andrea , Rodríguez, Armando , Vidal, Solange , Preising, Nico , Ständker, Ludger , Wiese, Sebastian , Stürzel, Christina M. , Harms, Mirja , Gross, Rüdiger , Jung, Christoph , Kiene, Miriam , Jacob, Timo , Pöhlmann, Stefan , Forssmann, Wolf-Georg , Münch, Jan , Sparrer, Konstantin M. J. , Seuwen, Klaus , Hahn, Beatrice H. and Kirchhoff, Frank
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
GPR15 is a G protein-coupled receptor (GPCR) proposed to play a role in mucosal immunity that also serves as a major entry cofactor for HIV-2 and simian immunodeficiency virus (SIV). To discover novel endogenous GPR15 ligands, we screened a hemofiltrate (HF)-derived peptide library for inhibitors of GPR15-mediated SIV infection. Our approach identi...
Alternative Titles
Full title
Natural cystatin C fragments inhibit GPR15-mediated HIV and SIV infection without interfering with GPR15L signaling
Authors, Artists and Contributors
Author / Creator
Blötz, Andrea
Rodríguez, Armando
Vidal, Solange
Preising, Nico
Ständker, Ludger
Wiese, Sebastian
Stürzel, Christina M.
Harms, Mirja
Gross, Rüdiger
Jung, Christoph
Kiene, Miriam
Jacob, Timo
Pöhlmann, Stefan
Forssmann, Wolf-Georg
Münch, Jan
Sparrer, Konstantin M. J.
Seuwen, Klaus
Hahn, Beatrice H.
Kirchhoff, Frank
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7826402
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7826402
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2023776118
