Nuclear miR-30b-5p suppresses TFEB-mediated lysosomal biogenesis and autophagy
Nuclear miR-30b-5p suppresses TFEB-mediated lysosomal biogenesis and autophagy
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Author / Creator
Guo, Huijie , Pu, Mei , Tai, Yusi , Chen, Yuxiang , Lu, Henglei , Qiao, Junwen , Wang, Guanghui , Chen, Jing , Qi, Xinming , Huang, Ruimin , Tao, Zhouteng and Ren, Jin
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Lysosome is a crucial organelle in charge of degrading proteins and damaged organelles to maintain cellular homeostasis. Transcription factor EB (TFEB) is the master transcription factor regulating lysosomal biogenesis and autophagy. Under external stimuli such as starvation, dephosphorylated TFEB transports into the nucleus to specifically recogni...
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Full title
Nuclear miR-30b-5p suppresses TFEB-mediated lysosomal biogenesis and autophagy
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7853097
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7853097
Other Identifiers
ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/s41418-020-0602-4
