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Maternal immune activation in mice disrupts proteostasis in the fetal brain

Maternal immune activation in mice disrupts proteostasis in the fetal brain

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7854524

Maternal immune activation in mice disrupts proteostasis in the fetal brain

About this item

Full title

Maternal immune activation in mice disrupts proteostasis in the fetal brain

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2021-02, Vol.24 (2), p.204-213

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Maternal infection and inflammation during pregnancy are associated with neurodevelopmental disorders in offspring, but little is understood about the molecular mechanisms underlying this epidemiologic phenomenon. Here, we leveraged single-cell RNA sequencing to profile transcriptional changes in the mouse fetal brain in response to maternal immune...

Alternative Titles

Full title

Maternal immune activation in mice disrupts proteostasis in the fetal brain

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7854524

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7854524

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/s41593-020-00762-9

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