Measuring DNA mechanics on the genome scale
Measuring DNA mechanics on the genome scale
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Mechanical deformations of DNA such as bending are ubiquitous and have been implicated in diverse cellular functions
1
. However, the lack of high-throughput tools to measure the mechanical properties of DNA has limited our understanding of how DNA mechanics influence chromatin transactions across the genome. Here we develop ‘loop-seq’—a high...
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Full title
Measuring DNA mechanics on the genome scale
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7855230
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7855230
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ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-020-03052-3