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Measuring DNA mechanics on the genome scale

Measuring DNA mechanics on the genome scale

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7855230

Measuring DNA mechanics on the genome scale

About this item

Full title

Measuring DNA mechanics on the genome scale

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2021-01, Vol.589 (7842), p.462-467

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Mechanical deformations of DNA such as bending are ubiquitous and have been implicated in diverse cellular functions
1
. However, the lack of high-throughput tools to measure the mechanical properties of DNA has limited our understanding of how DNA mechanics influence chromatin transactions across the genome. Here we develop ‘loop-seq’—a high...

Alternative Titles

Full title

Measuring DNA mechanics on the genome scale

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7855230

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7855230

Other Identifiers

ISSN

0028-0836,1476-4687

E-ISSN

1476-4687

DOI

10.1038/s41586-020-03052-3

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