DNA damage repair as a target in pancreatic cancer: state-of-the-art and future perspectives
DNA damage repair as a target in pancreatic cancer: state-of-the-art and future perspectives
About this item
Full title
Author / Creator
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title
Language
English
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Publication information
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Subjects
More information
Scope and Contents
Contents
Complex rearrangement patterns and mitotic errors are hallmarks of most pancreatic ductal adenocarcinomas (PDAC), a disease with dismal prognosis despite some therapeutic advances in recent years. DNA double-strand breaks (DSB) bear the greatest risk of provoking genomic instability, and DNA damage repair (DDR) pathways are crucial in preserving ge...
Alternative Titles
Full title
DNA damage repair as a target in pancreatic cancer: state-of-the-art and future perspectives
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7873425
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7873425
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2019-319984
