Staphylococcal protein A inhibits complement activation by interfering with IgG hexamer formation
Staphylococcal protein A inhibits complement activation by interfering with IgG hexamer formation
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Author / Creator
Cruz, Ana Rita , den Boer, Maurits A. , Strasser, Jürgen , Zwarthoff, Seline A. , Beurskens, Frank J. , de Haas, Carla J. C. , Aerts, Piet C. , Wang, Guanbo , de Jong, Rob N. , Bagnoli, Fabio , van Strijp, Jos A. G. , van Kessel, Kok P. M. , Schuurman, Janine , Preiner, Johannes , Heck, Albert J. R. and Rooijakkers, Suzan H. M.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Immunoglobulin (Ig) G molecules are essential players in the human immune response against bacterial infections. An important effector of IgG-dependent immunity is the induction of complement activation, a reaction that triggers a variety of responses that help kill bacteria. Antibody-dependent complement activation is promoted by the organization...
Alternative Titles
Full title
Staphylococcal protein A inhibits complement activation by interfering with IgG hexamer formation
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7896290
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7896290
Other Identifiers
ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.2016772118
