TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling
TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling
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Publisher
Cham: Springer International Publishing
Journal title
Language
English
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Cham: Springer International Publishing
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Scope and Contents
Contents
Toll-like receptor (TLR) 4 belongs to the TLR family of receptors inducing pro-inflammatory responses to invading pathogens. TLR4 is activated by lipopolysaccharide (LPS, endotoxin) of Gram-negative bacteria and sequentially triggers two signaling cascades: the first one involving TIRAP and MyD88 adaptor proteins is induced in the plasma membrane,...
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Full title
TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7904555
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7904555
Other Identifiers
ISSN
1420-682X
E-ISSN
1420-9071
DOI
10.1007/s00018-020-03656-y
