Increased Bone Resorption during Lactation in Pycnodysostosis
Increased Bone Resorption during Lactation in Pycnodysostosis
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Publisher
Switzerland: MDPI
Journal title
Language
English
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Publication information
Publisher
Switzerland: MDPI
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Scope and Contents
Contents
Pycnodysostosis, a rare autosomal recessive skeletal dysplasia, is caused by a deficiency of cathepsin K. Patients have impaired bone resorption in the presence of normal or increased numbers of multinucleated, but dysfunctional, osteoclasts. Cathepsin K degrades collagen type I and generates N-telopeptide (NTX) and the C-telopeptide (CTX) that can...
Alternative Titles
Full title
Increased Bone Resorption during Lactation in Pycnodysostosis
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7918824
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7918824
Other Identifiers
ISSN
1422-0067
E-ISSN
1422-0067
DOI
10.3390/ijms22041810
