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Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7948516

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

About this item

Full title

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Drug discovery, 2020-09, Vol.19 (9), p.609-633

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The brain requires a continuous supply of energy in the form of ATP, most of which is produced from glucose by oxidative phosphorylation in mitochondria, complemented by aerobic glycolysis in the cytoplasm. When glucose levels are limited, ketone bodies generated in the liver and lactate derived from exercising skeletal muscle can also become impor...

Alternative Titles

Full title

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7948516

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7948516

Other Identifiers

ISSN

1474-1776

E-ISSN

1474-1784

DOI

10.1038/s41573-020-0072-x

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