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A growth-factor-activated lysosomal K+ channel regulates Parkinson’s pathology

A growth-factor-activated lysosomal K+ channel regulates Parkinson’s pathology

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7979525

A growth-factor-activated lysosomal K+ channel regulates Parkinson’s pathology

About this item

Full title

A growth-factor-activated lysosomal K+ channel regulates Parkinson’s pathology

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2021-03, Vol.591 (7850), p.431-437

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Lysosomes have fundamental physiological roles and have previously been implicated in Parkinson’s disease
1

5
. However, how extracellular growth factors communicate with intracellular organelles to control lysosomal function is not well understood. Here we report a lysosomal K
+
channel complex that is activated by growth facto...

Alternative Titles

Full title

A growth-factor-activated lysosomal K+ channel regulates Parkinson’s pathology

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7979525

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7979525

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-021-03185-z

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