Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications...
Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration
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Author / Creator
Fukuda, Shinichi , Varshney, Akhil , Fowler, Benjamin J. , Wang, Shao-bin , Narendran, Siddharth , Ambati, Kameshwari , Yasuma, Tetsuhiro , Magagnoli, Joseph , Leung, Hannah , Hirahara, Shuichiro , Nagasaka, Yosuke , Yasuma, Reo , Apicella, Ivana , Pereira, Felipe , Makin, Ryan D. , Magner, Eamonn , Liu, Xinan , Sun, Jian , Wang, Mo , Baker, Kirstie , Marion, Kenneth M. , Huang, Xiwen , Baghdasaryan, Elmira , Ambati, Meenakshi , Ambati, Vidya L. , Pandey, Akshat , Pandya, Lekha , Cummings, Tammy , Banerjee, Daipayan , Huang, Peirong , Yerramothu, Praveen , Tolstonog, Genrich V. , Held, Ulrike , Erwin, Jennifer A. , Paquola, Apua C. M. , Herdy, Joseph R. , Ogura, Yuichiro , Terasaki, Hiroko , Oshika, Tetsuro , Darwish, Shaban , Singh, Ramendra K. , Mozaffari, Saghar , Bhattarai, Deepak , Kim, Kyung Bo , Hardin, James W. , Bennett, Charles L. , Hinton, David R. , Hanson, Timothy E. , Röver, Christian , Parang, Keykavous , Kerur, Nagaraj , Liu, Jinze , Werner, Brian C. , Sutton, S.Scott , Sadda, Srinivas R. , Schumann, Gerald G. , Gelfand, Bradley D. , Gage, Fred H. and Ambati, Jayakrishna
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Alu retroelements propagate via retrotransposition by hijacking long interspersed nuclear element-1 (L1) reverse transcriptase (RT) and endonuclease activities. Reverse transcription of Alu RNA into complementary DNA (cDNA) is presumed to occur exclusively in the nucleus at the genomic integration site. Whether Alu cDNA is synthesized independently...
Alternative Titles
Full title
Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration
Authors, Artists and Contributors
Author / Creator
Varshney, Akhil
Fowler, Benjamin J.
Wang, Shao-bin
Narendran, Siddharth
Ambati, Kameshwari
Yasuma, Tetsuhiro
Magagnoli, Joseph
Leung, Hannah
Hirahara, Shuichiro
Nagasaka, Yosuke
Yasuma, Reo
Apicella, Ivana
Pereira, Felipe
Makin, Ryan D.
Magner, Eamonn
Liu, Xinan
Sun, Jian
Wang, Mo
Baker, Kirstie
Marion, Kenneth M.
Huang, Xiwen
Baghdasaryan, Elmira
Ambati, Meenakshi
Ambati, Vidya L.
Pandey, Akshat
Pandya, Lekha
Cummings, Tammy
Banerjee, Daipayan
Huang, Peirong
Yerramothu, Praveen
Tolstonog, Genrich V.
Held, Ulrike
Erwin, Jennifer A.
Paquola, Apua C. M.
Herdy, Joseph R.
Ogura, Yuichiro
Terasaki, Hiroko
Oshika, Tetsuro
Darwish, Shaban
Singh, Ramendra K.
Mozaffari, Saghar
Bhattarai, Deepak
Kim, Kyung Bo
Hardin, James W.
Bennett, Charles L.
Hinton, David R.
Hanson, Timothy E.
Röver, Christian
Parang, Keykavous
Kerur, Nagaraj
Liu, Jinze
Werner, Brian C.
Sutton, S.Scott
Sadda, Srinivas R.
Schumann, Gerald G.
Gelfand, Bradley D.
Gage, Fred H.
Ambati, Jayakrishna
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8017980
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8017980
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2022751118
