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Interleukin 7 regulates switch transcription in developing B cells

Interleukin 7 regulates switch transcription in developing B cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8027593

Interleukin 7 regulates switch transcription in developing B cells

About this item

Full title

Interleukin 7 regulates switch transcription in developing B cells

Publisher

London: Nature Publishing Group UK

Journal title

Cellular & molecular immunology, 2021-03, Vol.18 (3), p.776-778

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Class switch recombination (CSR) enables activated mature B cells to change immunoglobulin (Ig) isotype expression from IgM to IgG, IgE, or IgA. The process requires activation-induced cytidine deaminase (AID) expression and transcription of the target sequences at the Ig heavy chain (IgH) constant locus, which is composed of multiple constant (CH)...

Alternative Titles

Full title

Interleukin 7 regulates switch transcription in developing B cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8027593

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8027593

Other Identifiers

ISSN

1672-7681

E-ISSN

2042-0226

DOI

10.1038/s41423-020-0430-y

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