Interleukin 7 regulates switch transcription in developing B cells
Interleukin 7 regulates switch transcription in developing B cells
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Class switch recombination (CSR) enables activated mature B cells to change immunoglobulin (Ig) isotype expression from IgM to IgG, IgE, or IgA. The process requires activation-induced cytidine deaminase (AID) expression and transcription of the target sequences at the Ig heavy chain (IgH) constant locus, which is composed of multiple constant (CH)...
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Full title
Interleukin 7 regulates switch transcription in developing B cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8027593
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8027593
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ISSN
1672-7681
E-ISSN
2042-0226
DOI
10.1038/s41423-020-0430-y