CD11c⁺CD88⁺CD317⁺ myeloid cells are critical mediators of persistent CNS autoimmunity
CD11c⁺CD88⁺CD317⁺ myeloid cells are critical mediators of persistent CNS autoimmunity
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Natalizumab, a humanized monoclonal antibody (mAb) against α4-integrin, reduces the number of dendritic cells (DC) in cerebral perivascular spaces in multiple sclerosis (MS). Selective deletion of α4-integrin in CD11c⁺ cells should curtail their migration to the central nervous system (CNS) and ameliorate experimental autoimmune encephalomyelitis (...
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Full title
CD11c⁺CD88⁺CD317⁺ myeloid cells are critical mediators of persistent CNS autoimmunity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8040603
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8040603
Other Identifiers
ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.2014492118
