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Is IL-6 a key cytokine target for therapy in COVID-19?

Is IL-6 a key cytokine target for therapy in COVID-19?

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8043092

Is IL-6 a key cytokine target for therapy in COVID-19?

About this item

Full title

Is IL-6 a key cytokine target for therapy in COVID-19?

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Immunology, 2021-06, Vol.21 (6), p.337-339

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The identification of elevated IL-6 levels in patients with severe COVID-19 led to the rapid development of clinical trials targeting this cytokine. Overall, these trials do not support the widespread use of IL-6 antagonists in hospitalized patients with mild-to-moderate disease, but IL-6 antagonists may be beneficial when rapidly deployed in patie...

Alternative Titles

Full title

Is IL-6 a key cytokine target for therapy in COVID-19?

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8043092

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8043092

Other Identifiers

ISSN

1474-1733

E-ISSN

1474-1741

DOI

10.1038/s41577-021-00553-8

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