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Achieving clinical success with BET inhibitors as anti-cancer agents

Achieving clinical success with BET inhibitors as anti-cancer agents

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8076232

Achieving clinical success with BET inhibitors as anti-cancer agents

About this item

Full title

Achieving clinical success with BET inhibitors as anti-cancer agents

Publisher

London: Nature Publishing Group UK

Journal title

British journal of cancer, 2021-04, Vol.124 (9), p.1478-1490

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The transcriptional upregulation of oncogenes is a driving force behind the progression of many tumours. However, until a decade ago, the concept of ‘switching off’ these oncogenic pathways represented a formidable challenge. Research has revealed that members of the bromo- and extra-terminal domain (BET) motif family are key activators of oncogeni...

Alternative Titles

Full title

Achieving clinical success with BET inhibitors as anti-cancer agents

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8076232

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8076232

Other Identifiers

ISSN

0007-0920

E-ISSN

1532-1827

DOI

10.1038/s41416-021-01321-0

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