Achieving clinical success with BET inhibitors as anti-cancer agents
Achieving clinical success with BET inhibitors as anti-cancer agents
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
The transcriptional upregulation of oncogenes is a driving force behind the progression of many tumours. However, until a decade ago, the concept of ‘switching off’ these oncogenic pathways represented a formidable challenge. Research has revealed that members of the bromo- and extra-terminal domain (BET) motif family are key activators of oncogeni...
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Full title
Achieving clinical success with BET inhibitors as anti-cancer agents
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8076232
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8076232
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ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/s41416-021-01321-0