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Tumoural activation of TLR3–SLIT2 axis in endothelium drives metastasis

Tumoural activation of TLR3–SLIT2 axis in endothelium drives metastasis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8088828

Tumoural activation of TLR3–SLIT2 axis in endothelium drives metastasis

About this item

Full title

Tumoural activation of TLR3–SLIT2 axis in endothelium drives metastasis

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2020-10, Vol.586 (7828), p.299-304

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Blood vessels support tumours by providing nutrients and oxygen, while also acting as conduits for the dissemination of cancer
1
. Here we use mouse models of breast and lung cancer to investigate whether endothelial cells also have active ‘instructive’ roles in the dissemination of cancer. We purified genetically tagged endothelial ribosomes...

Alternative Titles

Full title

Tumoural activation of TLR3–SLIT2 axis in endothelium drives metastasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8088828

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8088828

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-020-2774-y

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