PIP₂ corrects cerebral blood flow deficits in small vessel disease by rescuing capillary Kir2.1 acti...
PIP₂ corrects cerebral blood flow deficits in small vessel disease by rescuing capillary Kir2.1 activity
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Publisher
Washington: National Academy of Sciences
Journal title
Language
English
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Publisher
Washington: National Academy of Sciences
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Scope and Contents
Contents
Cerebral small vessel diseases (SVDs) are a central link between stroke and dementia—two comorbidities without specific treatments. Despite the emerging consensus that SVDs are initiated in the endothelium, the early mechanisms remain largely unknown. Deficits in on-demand delivery of blood to active brain regions (functional hyperemia) are early m...
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Full title
PIP₂ corrects cerebral blood flow deficits in small vessel disease by rescuing capillary Kir2.1 activity
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8092380
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8092380
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2025998118
