Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network t...
Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance
About this item
Full title
Author / Creator
Aschenbrenner, Dominik , Quaranta, Maria , Banerjee, Soumya , Ilott, Nicholas , Jansen, Joanneke , Steere, Boyd , Chen, Yin-Huai , Ho, Stephen , Cox, Karen , Arancibia-Cárcamo, Carolina V , Coles, Mark , Gaffney, Eamonn , Travis, Simon PL , Denson, Lee , Kugathasan, Subra , Schmitz, Jochen , Powrie, Fiona , Sansom, Stephen N and Uhlig, Holm H
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Subjects
More information
Scope and Contents
Contents
ObjectiveDysregulated immune responses are the cause of IBDs. Studies in mice and humans suggest a central role of interleukin (IL)-23-producing mononuclear phagocytes in disease pathogenesis. Mechanistic insights into the regulation of IL-23 are prerequisite for selective IL-23 targeting therapies as part of personalised medicine.DesignWe performe...
Alternative Titles
Full title
Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance
Authors, Artists and Contributors
Author / Creator
Quaranta, Maria
Banerjee, Soumya
Ilott, Nicholas
Jansen, Joanneke
Steere, Boyd
Chen, Yin-Huai
Ho, Stephen
Cox, Karen
Arancibia-Cárcamo, Carolina V
Coles, Mark
Gaffney, Eamonn
Travis, Simon PL
Denson, Lee
Kugathasan, Subra
Schmitz, Jochen
Powrie, Fiona
Sansom, Stephen N
Uhlig, Holm H
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8108288
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8108288
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2020-321731
