Long-term maturation of human cortical organoids matches key early postnatal transitions
Long-term maturation of human cortical organoids matches key early postnatal transitions
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Human stem-cell-derived models provide the promise of accelerating our understanding of brain disorders, but not knowing whether they possess the ability to mature beyond mid- to late-fetal stages potentially limits their utility. We leveraged a directed differentiation protocol to comprehensively assess maturation in vitro. Based on genome-wide an...
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Full title
Long-term maturation of human cortical organoids matches key early postnatal transitions
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8109149
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8109149
Other Identifiers
ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/s41593-021-00802-y
