[11C]MODAG-001—towards a PET tracer targeting α-synuclein aggregates
[11C]MODAG-001—towards a PET tracer targeting α-synuclein aggregates
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Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Berlin/Heidelberg: Springer Berlin Heidelberg
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Purpose
Deposition of misfolded alpha-synuclein (αSYN) aggregates in the human brain is one of the major hallmarks of synucleinopathies. However, a target-specific tracer to detect pathological aggregates of αSYN remains lacking. Here, we report the development of a positron emission tomography (PET) tracer based on anle138b, a compound shown to...
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Full title
[11C]MODAG-001—towards a PET tracer targeting α-synuclein aggregates
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8113290
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8113290
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ISSN
1619-7070
E-ISSN
1619-7089
DOI
10.1007/s00259-020-05133-x