Pyrroloquinoline quinone promotes mitochondrial biogenesis in rotenone-induced Parkinson’s disease m...
Pyrroloquinoline quinone promotes mitochondrial biogenesis in rotenone-induced Parkinson’s disease model via AMPK activation
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Author / Creator
Cheng, Qiong , Chen, Juan , Guo, Hui , Lu, Jin-li , Zhou, Jing , Guo, Xin-yu , Shi, Yue , Zhang, Yu , Yu, Shu , Zhang, Qi and Ding, Fei
Publisher
Singapore: Springer Singapore
Journal title
Language
English
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Publisher
Singapore: Springer Singapore
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Contents
Mitochondrial dysfunction is considered to be one of the important pathogenesis in Parkinson’s disease (PD). We previously showed that pyrroloquinoline quinone (PQQ) could protect SH-SY5Y cells and dopaminergic neurons from cytotoxicity and prevent mitochondrial dysfunction in rotenone-induced PD models. In the present study we investigated the mec...
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Full title
Pyrroloquinoline quinone promotes mitochondrial biogenesis in rotenone-induced Parkinson’s disease model via AMPK activation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8115282
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8115282
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ISSN
1671-4083
E-ISSN
1745-7254
DOI
10.1038/s41401-020-0487-2