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VPS35 D620N knockin mice recapitulate cardinal features of Parkinson’s disease

VPS35 D620N knockin mice recapitulate cardinal features of Parkinson’s disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8135078

VPS35 D620N knockin mice recapitulate cardinal features of Parkinson’s disease

About this item

Full title

VPS35 D620N knockin mice recapitulate cardinal features of Parkinson’s disease

Publisher

England: John Wiley & Sons, Inc

Journal title

Aging cell, 2021-05, Vol.20 (5), p.e13347-n/a

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

D620N mutation in the vacuolar protein sorting 35 ortholog (VPS35) gene causes late‐onset, autosomal dominant familial Parkinson's disease (PD) and contributes to idiopathic PD. However, how D620N mutation leads to PD‐related deficits in vivo remains unclear. In the present study, we thoroughly characterized the biochemical, pathological, and behav...

Alternative Titles

Full title

VPS35 D620N knockin mice recapitulate cardinal features of Parkinson’s disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8135078

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8135078

Other Identifiers

ISSN

1474-9718

E-ISSN

1474-9726

DOI

10.1111/acel.13347

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