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Parkinson's disease–associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes
Author / Creator:Wang, Wenzhang ; Wang, Xinglong ; Fujioka, Hisashi ; Hoppel, Charles ; Whone, Alan L ; Caldwell, Maeve A ; Cullen, Peter J ; Liu, Jun ; Zhu, Xiongwei
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2016-01, Vol.22 (1), p.54-63
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The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity
Author / Creator:Wang, Wenzhang ; Wang, Luwen ; Lu, Junjie ; Siedlak, Sandra L ; Fujioka, Hisashi ; Liang, Jingjing ; Jiang, Sirui ; Ma, Xiaopin ; Jiang, Zhen ; da Rocha, Edroaldo Lummertz ; Sheng, Max ; Choi, Heewon ; Lerou, Paul H ; Li, Hu ; Wang, Xinglong
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2016-08, Vol.22 (8), p.869-878
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VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington’s disease
Author / Creator:Guo, Xing ; Sun, XiaoYan ; Hu, Di ; Wang, Ya-Juan ; Fujioka, Hisashi ; Vyas, Rajan ; Chakrapani, Sudha ; Joshi, Amit Umesh ; Luo, Yu ; Mochly-Rosen, Daria ; Qi, Xin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-08, Vol.7 (1), p.12646-12646, Article 12646
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Distinct roles of resident and nonresident macrophages in nonischemic cardiomyopathy
Author / Creator:Liao, Xudong ; Shen, Yuyan ; Zhang, Rongli ; Sugi, Keiki ; Vasudevan, Neelakantan T. ; Alaiti, M. Amer ; Sweet, David R. ; Zhou, Lin ; Qing, Yulan ; Gerson, Stanton L. ; Fu, Chen ; Wynshaw-Boris, Anthony ; Hu, Rui ; Schwartz, Martin A. ; Fujioka, Hisashi ; Richardson, Brian ; Cameron, Mark J. ; Hayashi, Hiroki ; Stamler, Jonathan S. ; Jain, Mukesh K.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-05, Vol.115 (20), p.E4661-E4669
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Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins
Author / Creator:Wang, Xinglong ; Su, Bo ; Siedlak, Sandra L ; Moreira, Paula I ; Fujioka, Hisashi ; Wang, Yang ; Casadesus, Gemma ; Zhu, Xiongwei
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (49), p.19318-19323
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VPS35 D620N knockin mice recapitulate cardinal features of Parkinson’s disease
Author / Creator:Niu, Mengyue ; Zhao, Fanpeng ; Bondelid, Karina ; Siedlak, Sandra L. ; Torres, Sandy ; Fujioka, Hisashi ; Wang, Wenzhang ; Liu, Jun ; Zhu, Xiongwei
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2021-05, Vol.20 (5), p.e13347-n/a
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P7C3-A20 treatment one year after TBI in mice repairs the blood–brain barrier, arrests chronic neurodegeneration, and restores cognition
Author / Creator:Vázquez-Rosa, Edwin ; Shin, Min-Kyoo ; Dhar, Matasha ; Chaubey, Kalyani ; Cintrón-Pérez, Coral J. ; Tang, Xinmiao ; Liao, Xudong ; Miller, Emiko ; Koh, Yeojung ; Barker, Sarah ; Franke, Kathryn ; Crosby, Danyel R. ; Schroeder, Rachel ; Emery, Josie ; Yin, Terry C. ; Fujioka, Hisashi ; Reynolds, James D. ; Harper, Matthew M. ; Jain, Mukesh K. ; Pieper, Andrew A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-11, Vol.117 (44), p.27667-27675
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Mitophagy is required for brown adipose tissue mitochondrial homeostasis during cold challenge
Author / Creator:Lu, Yuan ; Fujioka, Hisashi ; Joshi, Dinesh ; Li, Qiaoyuan ; Sangwung, Panjamaporn ; Hsieh, Paishiun ; Zhu, Jiyun ; Torio, Jose ; Sweet, David ; Wang, Lan ; Chiu, Shing Yan ; Croniger, Colleen ; Liao, Xudong ; Jain, Mukesh K.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-05, Vol.8 (1), p.8251-13, Article 8251
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Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex
Author / Creator:Jiang, Sirui ; Nandy, Priya ; Wang, Wenzhang ; Ma, Xiaopin ; Hsia, Jeffrey ; Wang, Chunyu ; Wang, Zhenlian ; Niu, Mengyue ; Siedlak, Sandra L. ; Torres, Sandy ; Fujioka, Hisashi ; Xu, Ying ; Lee, Hyoung-gon ; Perry, George ; Liu, Jun ; Zhu, Xiongwei
Publisher:England: BioMed Central Ltd
Journal title:Molecular neurodegeneration, 2018-02, Vol.13 (1), p.5-5, Article 5
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Damaged mitochondria coincide with presynaptic vesicle loss and abnormalities in alzheimer’s disease brain
Author / Creator:Wang, Wenzhang ; Zhao, Fanpeng ; Lu, Yubing ; Siedlak, Sandra L. ; Fujioka, Hisashi ; Feng, Hao ; Perry, George ; Zhu, Xiongwei
Publisher:England: BioMed Central Ltd
Journal title:Acta neuropathologica communications, 2023-03, Vol.11 (1), p.54-54, Article 54
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Kruppel-like factor 4 is critical for transcriptional control of cardiac mitochondrial homeostasis
Author / Creator:Liao, Xudong ; Zhang, Rongli ; Lu, Yuan ; Prosdocimo, Domenick A. ; Sangwung, Panjamaporn ; Zhang, Lilei ; Zhou, Guangjin ; Anand, Puneet ; Lai, Ling ; Leone, Teresa C. ; Fujioka, Hisashi ; Ye, Fang ; Rosca, Mariana G. ; Hoppel, Charles L. ; Schulze, P. Christian ; Abel, E. Dale ; Stamler, Jonathan S. ; Kelly, Daniel P. ; Jain, Mukesh K.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2015-09, Vol.125 (9), p.3461-3476
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A conserved KLF-autophagy pathway modulates nematode lifespan and mammalian age-associated vascular dysfunction
Author / Creator:Hsieh, Paishiun N. ; Zhou, Guangjin ; Yuan, Yiyuan ; Zhang, Rongli ; Prosdocimo, Domenick A. ; Sangwung, Panjamaporn ; Borton, Anna H. ; Boriushkin, Evgenii ; Hamik, Anne ; Fujioka, Hisashi ; Fealy, Ciaran E. ; Kirwan, John P. ; Peters, Maureen ; Lu, Yuan ; Liao, Xudong ; Ramírez-Bergeron, Diana ; Feng, Zhaoyang ; Jain, Mukesh K.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-10, Vol.8 (1), p.914-12, Article 914
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BAM15‐mediated mitochondrial uncoupling protects against obesity and improves glycemic control
Author / Creator:Axelrod, Christopher L ; King, William T ; Davuluri, Gangarao ; Noland, Robert C ; Hall, Jacob ; Hull, Michaela ; Dantas, Wagner S ; Zunica, Elizabeth RM ; Alexopoulos, Stephanie J ; Hoehn, Kyle L ; Langohr, Ingeborg ; Stadler, Krisztian ; Doyle, Haylee ; Schmidt, Eva ; Nieuwoudt, Stephan ; Fitzgerald, Kelly ; Pergola, Kathryn ; Fujioka, Hisashi ; Mey, Jacob T ; Fealy, Ciaran ; Mulya, Anny ; Beyl, Robbie ; Hoppel, Charles L ; Kirwan, John P
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2020-07, Vol.12 (7), p.e12088-n/a
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Mitochondrial uncoupling attenuates sarcopenic obesity by enhancing skeletal muscle mitophagy and quality control
Author / Creator:Dantas, Wagner S. ; Zunica, Elizabeth R.M. ; Heintz, Elizabeth C. ; Vandanmagsar, Bolormaa ; Floyd, Z. Elizabeth ; Yu, Yongmei ; Fujioka, Hisashi ; Hoppel, Charles L. ; Belmont, Kathryn P. ; Axelrod, Christopher L. ; Kirwan, John P.
Publisher:Germany: John Wiley & Sons, Inc
Journal title:Journal of cachexia, sarcopenia and muscle, 2022-06, Vol.13 (3), p.1821-1836
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Mfn2 Ablation in the Adult Mouse Hippocampus and Cortex Causes Neuronal Death
Author / Creator:Han, Song ; Nandy, Priya ; Austria, Quillan ; Siedlak, Sandra L. ; Torres, Sandy ; Fujioka, Hisashi ; Wang, Wenzhang ; Zhu, Xiongwei
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2020-01, Vol.9 (1), p.116
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Kruppel-like factor 15 regulates skeletal muscle lipid flux and exercise adaptation
Author / Creator:Haldar, Saptarsi M. ; Jeyaraj, Darwin ; Anand, Priti ; Zhu, Han ; Lu, Yuan ; Prosdocimo, Domenick A. ; Eapen, Betty ; Kawanami, Daiji ; Okutsu, Mitsuharu ; Brotto, Leticia ; Fujioka, Hisashi ; Kerner, Janos ; Rosca, Mariana G. ; McGuinness, Owen P. ; Snow, Rod J. ; Russell, Aaron P. ; Gerber, Anthony N. ; Bai, Xiaodong ; Yan, Zhen ; Nosek, Thomas M. ; Brotto, Marco ; Hoppel, Charles L. ; Jain, Mukesh K.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (17), p.6739-6744
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Fluorescent Nanoparticle Uptake by Myzocytosis and Endocytosis in Colpodella sp. ATCC 50594
Author / Creator:Sam-Yellowe, Tobili Y. ; Asraf, Mary M. ; Peterson, John W. ; Fujioka, Hisashi
Publisher:Basel: MDPI AG
Journal title:Microorganisms (Basel), 2023-07, Vol.11 (8), p.1945
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Impaired cytoadherence of Plasmodium falciparum-infected erythrocytes containing sickle hemoglobin
Author / Creator:Cholera, Rushina ; Brittain, Nathaniel J ; Gillrie, Mark R ; Lopera-Mesa, Tatiana M ; Diakité, Séidina A.S ; Arie, Takayuki ; Krause, Michael A ; Guindo, Aldiouma ; Tubman, Abby ; Fujioka, Hisashi ; Diallo, Dapa A ; Doumbo, Ogobara K ; Ho, May ; Wellems, Thomas E ; Fairhurst, Rick M
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2008-01, Vol.105 (3), p.991-996
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A Role for Fetal Hemoglobin and Maternal Immune IgG in Infant Resistance to Plasmodium falciparum Malaria
Author / Creator:Amaratunga, Chanaki ; Lopera-Mesa, Tatiana M. ; Brittain, Nathaniel J. ; Cholera, Rushina ; Arie, Takayuki ; Fujioka, Hisashi ; Keefer, Jeffrey R. ; Fairhurst, Rick M.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-04, Vol.6 (4), p.e14798-e14798
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Deubiquitinating Enzymes Regulate Skeletal Muscle Mitochondrial Quality Control and Insulin Sensitivity in Patients With Type 2 Diabetes
Author / Creator:Dantas, Wagner S. ; Heintz, Elizabeth C. ; Zunica, Elizabeth R. M. ; Mey, Jacob T. ; Erickson, Melissa L. ; Belmont, Kathryn P. ; Taylor, Analisa L. ; Davuluri, Gangarao ; Fujioka, Hisashi ; Fealy, Ciarán E. ; Hoppel, Charles L. ; Axelrod, Christopher L. ; Kirwan, John P.
Publisher:Germany: John Wiley & Sons, Inc
Journal title:Journal of cachexia, sarcopenia and muscle, 2025-04, Vol.16 (2), p.e13763-n/a
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Showing 1 to 20 of 50 results

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Parkinson's disease–associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes

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The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity

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VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington’s disease

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Distinct roles of resident and nonresident macrophages in nonischemic cardiomyopathy

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Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

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VPS35 D620N knockin mice recapitulate cardinal features of Parkinson’s disease

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P7C3-A20 treatment one year after TBI in mice repairs the blood–brain barrier, arrests chronic neurodegeneration, and restores cognition

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Mitophagy is required for brown adipose tissue mitochondrial homeostasis during cold challenge

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Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex

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Damaged mitochondria coincide with presynaptic vesicle loss and abnormalities in alzheimer’s disease brain

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Kruppel-like factor 4 is critical for transcriptional control of cardiac mitochondrial homeostasis

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A conserved KLF-autophagy pathway modulates nematode lifespan and mammalian age-associated vascular dysfunction

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BAM15‐mediated mitochondrial uncoupling protects against obesity and improves glycemic control

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Mitochondrial uncoupling attenuates sarcopenic obesity by enhancing skeletal muscle mitophagy and quality control

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Mfn2 Ablation in the Adult Mouse Hippocampus and Cortex Causes Neuronal Death

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Kruppel-like factor 15 regulates skeletal muscle lipid flux and exercise adaptation

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Fluorescent Nanoparticle Uptake by Myzocytosis and Endocytosis in Colpodella sp. ATCC 50594

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Impaired cytoadherence of Plasmodium falciparum-infected erythrocytes containing sickle hemoglobin

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A Role for Fetal Hemoglobin and Maternal Immune IgG in Infant Resistance to Plasmodium falciparum Malaria

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Deubiquitinating Enzymes Regulate Skeletal Muscle Mitochondrial Quality Control and Insulin Sensitivity in Patients With Type 2 Diabetes

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