Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal
Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal
About this item
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Author / Creator
Sun, Wan-Yang , Tyurin, Vladimir A. , Mikulska-Ruminska, Karolina , Shrivastava, Indira H. , Anthonymuthu, Tamil S. , Zhai, Yu-Jia , Pan, Ming-Hai , Gong, Hai-Biao , Lu, Dan-Hua , Sun, Jie , Duan, Wen-Jun , Korolev, Sergey , Abramov, Andrey Y. , Angelova, Plamena R. , Miller, Ian , Beharier, Ofer , Mao, Gao-Wei , Dar, Haider H. , Kapralov, Alexandr A. , Amoscato, Andrew A. , Hastings, Teresa G. , Greenamyre, Timothy J. , Chu, Charleen T. , Sadovsky, Yoel , Bahar, Ivet , Bayır, Hülya , Tyurina, Yulia Y. , He, Rong-Rong and Kagan, Valerian E.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Ferroptosis, triggered by discoordination of iron, thiols and lipids, leads to the accumulation of 15-hydroperoxy (Hp)-arachidonoyl-phosphatidylethanolamine (15-HpETE-PE), generated by complexes of 15-lipoxygenase (15-LOX) and a scaffold protein, phosphatidylethanolamine (PE)-binding protein (PEBP)1. As the Ca
2+
-independent phospholipase A<...
Alternative Titles
Full title
Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal
Authors, Artists and Contributors
Author / Creator
Tyurin, Vladimir A.
Mikulska-Ruminska, Karolina
Shrivastava, Indira H.
Anthonymuthu, Tamil S.
Zhai, Yu-Jia
Pan, Ming-Hai
Gong, Hai-Biao
Lu, Dan-Hua
Sun, Jie
Duan, Wen-Jun
Korolev, Sergey
Abramov, Andrey Y.
Angelova, Plamena R.
Miller, Ian
Beharier, Ofer
Mao, Gao-Wei
Dar, Haider H.
Kapralov, Alexandr A.
Amoscato, Andrew A.
Hastings, Teresa G.
Greenamyre, Timothy J.
Chu, Charleen T.
Sadovsky, Yoel
Bahar, Ivet
Bayır, Hülya
Tyurina, Yulia Y.
He, Rong-Rong
Kagan, Valerian E.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8152680
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8152680
Other Identifiers
ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/s41589-020-00734-x
