RABL6A Regulates Schwann Cell Senescence in an RB1-Dependent Manner
RABL6A Regulates Schwann Cell Senescence in an RB1-Dependent Manner
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Publisher
Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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Schwann cells are normally quiescent, myelinating glia cells of the peripheral nervous system. Their aberrant proliferation and transformation underlie the development of benign tumors (neurofibromas) as well as deadly malignant peripheral nerve sheath tumors (MPNSTs). We discovered a new driver of MPNSTs, an oncogenic GTPase named RABL6A, that fun...
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RABL6A Regulates Schwann Cell Senescence in an RB1-Dependent Manner
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8161079
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8161079
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms22105367
