A PRC2-independent function for EZH2 in regulating rRNA 2′-O methylation and IRES-dependent translat...
A PRC2-independent function for EZH2 in regulating rRNA 2′-O methylation and IRES-dependent translation
About this item
Full title
Author / Creator
Yi, Yang , Li, Yanqiang , Meng, Qingshu , Li, Qiaqia , Li, Fuxi , Lu, Bing , Shen, Jiangchuan , Fazli, Ladan , Zhao, Dongyu , Li, Chao , Jiang, Weihua , Wang, Rui , Liu, Qipeng , Szczepanski, Aileen , Li, Qianru , Qin, Wei , Weiner, Adam B. , Lotan, Tamara L. , Ji, Zhe , Kalantry, Sundeep , Wang, Lu , Schaeffer, Edward M. , Niu, Hengyao , Dong, Xuesen , Zhao, Wei , Chen, Kaifu and Cao, Qi
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Dysregulated translation is a common feature of cancer. Uncovering its governing factors and underlying mechanism are important for cancer therapy. Here, we report that enhancer of zeste homologue 2 (EZH2), previously known as a transcription repressor and lysine methyltransferase, can directly interact with fibrillarin (FBL) to exert its role in t...
Alternative Titles
Full title
A PRC2-independent function for EZH2 in regulating rRNA 2′-O methylation and IRES-dependent translation
Authors, Artists and Contributors
Author / Creator
Li, Yanqiang
Meng, Qingshu
Li, Qiaqia
Li, Fuxi
Lu, Bing
Shen, Jiangchuan
Fazli, Ladan
Zhao, Dongyu
Li, Chao
Jiang, Weihua
Wang, Rui
Liu, Qipeng
Szczepanski, Aileen
Li, Qianru
Qin, Wei
Weiner, Adam B.
Lotan, Tamara L.
Ji, Zhe
Kalantry, Sundeep
Wang, Lu
Schaeffer, Edward M.
Niu, Hengyao
Dong, Xuesen
Zhao, Wei
Chen, Kaifu
Cao, Qi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8162121
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8162121
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/s41556-021-00653-6
