Anti-BCMA CAR T-Cell Therapy bb2121 in Relapsed or Refractory Multiple Myeloma
Anti-BCMA CAR T-Cell Therapy bb2121 in Relapsed or Refractory Multiple Myeloma
About this item
Full title
Author / Creator
Raje, Noopur , Berdeja, Jesus , Lin, Yi , Siegel, David , Jagannath, Sundar , Madduri, Deepu , Liedtke, Michaela , Rosenblatt, Jacalyn , Maus, Marcela V , Turka, Ashley , Lam, Lyh-Ping , Morgan, Richard A , Friedman, Kevin , Massaro, Monica , Wang, Julie , Russotti, Greg , Yang, Zhihong , Campbell, Timothy , Hege, Kristen , Petrocca, Fabio , Quigley, M. Travis , Munshi, Nikhil and Kochenderfer, James N
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Chimeric antigen receptor autologous T cells that were directed against the B-cell maturation antigen induced responses in 85% of the 33 patients with relapsed or refractory myeloma in whom they were infused only once. The frequency and severity of cytokine release syndrome were less than have been seen with other CAR T cells.
Alternative Titles
Full title
Anti-BCMA CAR T-Cell Therapy bb2121 in Relapsed or Refractory Multiple Myeloma
Authors, Artists and Contributors
Author / Creator
Berdeja, Jesus
Lin, Yi
Siegel, David
Jagannath, Sundar
Madduri, Deepu
Liedtke, Michaela
Rosenblatt, Jacalyn
Maus, Marcela V
Turka, Ashley
Lam, Lyh-Ping
Morgan, Richard A
Friedman, Kevin
Massaro, Monica
Wang, Julie
Russotti, Greg
Yang, Zhihong
Campbell, Timothy
Hege, Kristen
Petrocca, Fabio
Quigley, M. Travis
Munshi, Nikhil
Kochenderfer, James N
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8202968
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8202968
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1817226
