Safety and Efficacy of Single-Dose Ad26.COV2.S Vaccine against Covid-19
Safety and Efficacy of Single-Dose Ad26.COV2.S Vaccine against Covid-19
About this item
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Author / Creator
ENSEMBLE Study Group , Sadoff, Jerald , Gray, Glenda , Vandebosch, An , Cárdenas, Vicky , Shukarev, Georgi , Grinsztejn, Beatriz , Goepfert, Paul A , Truyers, Carla , Fennema, Hein , Spiessens, Bart , Offergeld, Kim , Scheper, Gert , Taylor, Kimberly L , Robb, Merlin L , Treanor, John , Barouch, Dan H , Stoddard, Jeffrey , Ryser, Martin F , Marovich, Mary A , Neuzil, Kathleen M , Corey, Lawrence , Cauwenberghs, Nancy , Tanner, Tamzin , Hardt, Karin , Ruiz-Guiñazú, Javier , Le Gars, Mathieu , Schuitemaker, Hanneke , Van Hoof, Johan , Struyf, Frank and Douoguih, Macaya
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Ad26.COV2.S vaccine is a replication-incompetent human adenovirus type 26 vector containing the gene sequence that produces SARS-CoV-2 spike protein in a prefusion-stabilized conformation. In a randomized trial involving nearly 40,000 persons, vaccine efficacy was 66% against moderate to severe–critical Covid-19 and 85% against severe–critical Covi...
Alternative Titles
Full title
Safety and Efficacy of Single-Dose Ad26.COV2.S Vaccine against Covid-19
Authors, Artists and Contributors
Author / Creator
Sadoff, Jerald
Gray, Glenda
Vandebosch, An
Cárdenas, Vicky
Shukarev, Georgi
Grinsztejn, Beatriz
Goepfert, Paul A
Truyers, Carla
Fennema, Hein
Spiessens, Bart
Offergeld, Kim
Scheper, Gert
Taylor, Kimberly L
Robb, Merlin L
Treanor, John
Barouch, Dan H
Stoddard, Jeffrey
Ryser, Martin F
Marovich, Mary A
Neuzil, Kathleen M
Corey, Lawrence
Cauwenberghs, Nancy
Tanner, Tamzin
Hardt, Karin
Ruiz-Guiñazú, Javier
Le Gars, Mathieu
Schuitemaker, Hanneke
Van Hoof, Johan
Struyf, Frank
Douoguih, Macaya
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8220996
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8220996
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa2101544
