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Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization

Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8221230

Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization

About this item

Full title

Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization

Author / Creator

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Molecular cell biology, 2021-04, Vol.22 (4), p.283-298

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The regulation of telomere length in mammals is crucial for chromosome end-capping and thus for maintaining genome stability and cellular lifespan. This process requires coordination between telomeric protein complexes and the ribonucleoprotein telomerase, which extends the telomeric DNA. Telomeric proteins modulate telomere architecture, recruit t...

Alternative Titles

Full title

Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8221230

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8221230

Other Identifiers

ISSN

1471-0072

E-ISSN

1471-0080

DOI

10.1038/s41580-021-00328-y

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