Analysis of NHEJ-Based DNA Repair after CRISPR-Mediated DNA Cleavage
Analysis of NHEJ-Based DNA Repair after CRISPR-Mediated DNA Cleavage
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Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
Genome editing using CRISPR-Cas9 nucleases is based on the repair of the DNA double-strand break (DSB). In eukaryotic cells, DSBs are rejoined through homology-directed repair (HDR), non-homologous end joining (NHEJ) or microhomology-mediated end joining (MMEJ) pathways. Among these, it is thought that the NHEJ pathway is dominant and occurs throug...
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Full title
Analysis of NHEJ-Based DNA Repair after CRISPR-Mediated DNA Cleavage
Authors, Artists and Contributors
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8232687
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8232687
Other Identifiers
ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms22126397
