Dexamethasone suppresses immune evasion by inducing GR/STAT3 mediated downregulation of PD-L1 and ID...
Dexamethasone suppresses immune evasion by inducing GR/STAT3 mediated downregulation of PD-L1 and IDO1 pathways
About this item
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Author / Creator
Xiang, Zhen , Zhou, Zhijun , Song, Shuzheng , Li, Jun , Ji, Jun , Yan, Ranlin , Wang, Jiexuan , Cai, Wei , Hu, Wenjun , Zang, Lu , Zhu, Zhenggang , Zhang, Zhen , Li, Min and Yu, Yingyan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
T cell exhaustion plays critical roles in tumor immune evasion. Novel strategies to suppress immune evasion are in urgent need. We aimed to identify potential compounds to target T cell exhaustion and increase response to immune checkpoint inhibitors (ICIs). Differentially expressed genes (DEGs) were identified between tumors with different immune...
Alternative Titles
Full title
Dexamethasone suppresses immune evasion by inducing GR/STAT3 mediated downregulation of PD-L1 and IDO1 pathways
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8235907
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8235907
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-021-01897-0
