Basophils balance healing after myocardial infarction via IL-4/IL-13
Basophils balance healing after myocardial infarction via IL-4/IL-13
About this item
Full title
Author / Creator
Sicklinger, Florian , Meyer, Ingmar Sören , Li, Xue , Radtke, Daniel , Dicks, Severin , Kornadt, Moritz P , Mertens, Christina , Meier, Julia K , Lavine, Kory J , Zhang, Yunhang , Kuhn, Tim Christian , Terzer, Tobias , Patel, Jyoti , Boerries, Melanie , Schramm, Gabriele , Frey, Norbert , Katus, Hugo A , Voehringer, David and Leuschner, Florian
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
The inflammatory response after myocardial infarction (MI) is a precisely regulated process that greatly affects subsequent remodeling. Here, we show that basophil granulocytes infiltrated infarcted murine hearts, with a peak occurring between days 3 and 7. Antibody-mediated and genetic depletion of basophils deteriorated cardiac function and resul...
Alternative Titles
Full title
Basophils balance healing after myocardial infarction via IL-4/IL-13
Authors, Artists and Contributors
Author / Creator
Meyer, Ingmar Sören
Li, Xue
Radtke, Daniel
Dicks, Severin
Kornadt, Moritz P
Mertens, Christina
Meier, Julia K
Lavine, Kory J
Zhang, Yunhang
Kuhn, Tim Christian
Terzer, Tobias
Patel, Jyoti
Boerries, Melanie
Schramm, Gabriele
Frey, Norbert
Katus, Hugo A
Voehringer, David
Leuschner, Florian
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8245180
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8245180
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI136778
