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Precapillary sphincters and pericytes at first-order capillaries as key regulators for brain capilla...

Precapillary sphincters and pericytes at first-order capillaries as key regulators for brain capilla...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8255959

Precapillary sphincters and pericytes at first-order capillaries as key regulators for brain capillary perfusion

About this item

Full title

Precapillary sphincters and pericytes at first-order capillaries as key regulators for brain capillary perfusion

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2021-06, Vol.118 (26), p.1-10

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Rises in local neural activity trigger local increases of cerebral blood flow, which is essential to match local energy demands. However, the specific location of microvascular flow control is incompletely understood. Here, we used two-photon microscopy to observe brain microvasculature in vivo. Small spatial movement of a three-dimensional (3D) va...

Alternative Titles

Full title

Precapillary sphincters and pericytes at first-order capillaries as key regulators for brain capillary perfusion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8255959

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8255959

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.2023749118

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