Epithelial cell plasticity drives endoderm formation during gastrulation
Epithelial cell plasticity drives endoderm formation during gastrulation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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It is generally accepted that epiblast cells ingress into the primitive streak by epithelial-to-mesenchymal transition (EMT) to give rise to the mesoderm; however, it is less clear how the endoderm acquires an epithelial fate. Here, we used embryonic stem cell and mouse embryo knock‐in reporter systems to combine time-resolved lineage labelling wit...
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Epithelial cell plasticity drives endoderm formation during gastrulation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8277579
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8277579
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ISSN
1465-7392,1476-4679
E-ISSN
1476-4679
DOI
10.1038/s41556-021-00694-x