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Epithelial cell plasticity drives endoderm formation during gastrulation

Epithelial cell plasticity drives endoderm formation during gastrulation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8277579

Epithelial cell plasticity drives endoderm formation during gastrulation

About this item

Full title

Epithelial cell plasticity drives endoderm formation during gastrulation

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2021-07, Vol.23 (7), p.692-703

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

It is generally accepted that epiblast cells ingress into the primitive streak by epithelial-to-mesenchymal transition (EMT) to give rise to the mesoderm; however, it is less clear how the endoderm acquires an epithelial fate. Here, we used embryonic stem cell and mouse embryo knock‐in reporter systems to combine time-resolved lineage labelling wit...

Alternative Titles

Full title

Epithelial cell plasticity drives endoderm formation during gastrulation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8277579

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8277579

Other Identifiers

ISSN

1465-7392,1476-4679

E-ISSN

1476-4679

DOI

10.1038/s41556-021-00694-x

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