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Intracellular pH controls WNT downstream of glycolysis in amniote embryos

Intracellular pH controls WNT downstream of glycolysis in amniote embryos

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8278564

Intracellular pH controls WNT downstream of glycolysis in amniote embryos

About this item

Full title

Intracellular pH controls WNT downstream of glycolysis in amniote embryos

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2020-08, Vol.584 (7819), p.98-101

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Formation of the body of vertebrate embryos proceeds sequentially by posterior addition of tissues from the tail bud. Cells of the tail bud and the posterior presomitic mesoderm, which control posterior elongation
1
, exhibit a high level of aerobic glycolysis that is reminiscent of the metabolic status of cancer cells experiencing the Warbur...

Alternative Titles

Full title

Intracellular pH controls WNT downstream of glycolysis in amniote embryos

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8278564

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8278564

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-020-2428-0

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