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Regulation of the nucleic acid-sensing Toll-like receptors

Regulation of the nucleic acid-sensing Toll-like receptors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8283745

Regulation of the nucleic acid-sensing Toll-like receptors

About this item

Full title

Regulation of the nucleic acid-sensing Toll-like receptors

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Immunology, 2022-04, Vol.22 (4), p.224-235

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Many of the ligands for Toll-like receptors (TLRs) are unique to microorganisms, such that receptor activation unequivocally indicates the presence of something foreign. However, a subset of TLRs recognizes nucleic acids, which are present in both the host and foreign microorganisms. This specificity enables broad recognition by virtue of the ubiqu...

Alternative Titles

Full title

Regulation of the nucleic acid-sensing Toll-like receptors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8283745

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8283745

Other Identifiers

ISSN

1474-1733

E-ISSN

1474-1741

DOI

10.1038/s41577-021-00577-0

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