Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin...
Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Dynamin oligomerizes into helical filaments on tubular membrane templates and, through constriction, cleaves them in a GTPase-driven way. Structural observations of GTP-dependent cross-bridges between neighboring filament turns have led to the suggestion that dynamin operates as a molecular ratchet motor. However, the proof of such mechanism remain...
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Full title
Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8285958
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8285958
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ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.2101144118
