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Cellular senescence in ageing: from mechanisms to therapeutic opportunities

Cellular senescence in ageing: from mechanisms to therapeutic opportunities

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8344376

Cellular senescence in ageing: from mechanisms to therapeutic opportunities

About this item

Full title

Cellular senescence in ageing: from mechanisms to therapeutic opportunities

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Molecular cell biology, 2021-02, Vol.22 (2), p.75-95

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cellular senescence, first described in vitro in 1961, has become a focus for biotech companies that target it to ameliorate a variety of human conditions. Eminently characterized by a permanent proliferation arrest, cellular senescence occurs in response to endogenous and exogenous stresses, including telomere dysfunction, oncogene activation and...

Alternative Titles

Full title

Cellular senescence in ageing: from mechanisms to therapeutic opportunities

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8344376

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8344376

Other Identifiers

ISSN

1471-0072

E-ISSN

1471-0080

DOI

10.1038/s41580-020-00314-w

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