Cellular senescence in ageing: from mechanisms to therapeutic opportunities
Cellular senescence in ageing: from mechanisms to therapeutic opportunities
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Cellular senescence, first described in vitro in 1961, has become a focus for biotech companies that target it to ameliorate a variety of human conditions. Eminently characterized by a permanent proliferation arrest, cellular senescence occurs in response to endogenous and exogenous stresses, including telomere dysfunction, oncogene activation and...
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Full title
Cellular senescence in ageing: from mechanisms to therapeutic opportunities
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8344376
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8344376
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ISSN
1471-0072
E-ISSN
1471-0080
DOI
10.1038/s41580-020-00314-w