An open-source drug discovery platform enables ultra-large virtual screens
An open-source drug discovery platform enables ultra-large virtual screens
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Author / Creator
Gorgulla, Christoph , Boeszoermenyi, Andras , Wang, Zi-Fu , Fischer, Patrick D. , Coote, Paul W. , Padmanabha Das, Krishna M. , Malets, Yehor S. , Radchenko, Dmytro S. , Moroz, Yurii S. , Scott, David A. , Fackeldey, Konstantin , Hoffmann, Moritz , Iavniuk, Iryna , Wagner, Gerhard and Arthanari, Haribabu
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
On average, an approved drug currently costs US$2–3 billion and takes more than 10 years to develop
1
. In part, this is due to expensive and time-consuming wet-laboratory experiments, poor initial hit compounds and the high attrition rates in the (pre-)clinical phases. Structure-based virtual screening has the potential to mitigate these pro...
Alternative Titles
Full title
An open-source drug discovery platform enables ultra-large virtual screens
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8352709
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8352709
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2117-z
