Transcriptome-wide association study of treatment-resistant depression and depression subtypes for d...
Transcriptome-wide association study of treatment-resistant depression and depression subtypes for drug repurposing
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Author / Creator
Publisher
England: Nature Publishing Group
Journal title
Language
English
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Publisher
England: Nature Publishing Group
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Scope and Contents
Contents
Major depressive disorder (MDD) is the single largest contributor to global disability and up to 20-30% of patients do not respond to at least two antidepressants (treatment-resistant depression, TRD). This study leveraged imputed gene expression in TRD to perform a drug repurposing analysis. Among those with MDD, we defined TRD as having at least...
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Full title
Transcriptome-wide association study of treatment-resistant depression and depression subtypes for drug repurposing
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8357803
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8357803
Other Identifiers
ISSN
0893-133X
E-ISSN
1740-634X
DOI
10.1038/s41386-021-01059-6
