circPDE4B prevents articular cartilage degeneration and promotes repair by acting as a scaffold for...
circPDE4B prevents articular cartilage degeneration and promotes repair by acting as a scaffold for RIC8A and MID1
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Author / Creator
Shen, Shuying , Yang, Yute , Shen, Panyang , Ma, Jun , Fang, Bin , Wang, Qingxin , Wang, Kefan , Shi, Peihua , Fan, Shunwu and Fang, Xiangqian
Publisher
England: Elsevier Limited
Journal title
Language
English
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Publisher
England: Elsevier Limited
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Scope and Contents
Contents
ObjectivesCircular RNAs (circRNAs) have emerged as significant biological regulators. Herein, we aimed to elucidate the role of an unidentified circRNA (circPDE4B) that is reportedly downregulated in osteoarthritis (OA) tissues.MethodsThe effects of circPDE4B were explored in human and mouse chondrocytes in vitro. Specifically, RNA pull-down (RPD)-...
Alternative Titles
Full title
circPDE4B prevents articular cartilage degeneration and promotes repair by acting as a scaffold for RIC8A and MID1
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8372377
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8372377
Other Identifiers
ISSN
0003-4967
E-ISSN
1468-2060
DOI
10.1136/annrheumdis-2021-219969