Efficient Neuroprotective Rescue of Sacsin-Related Disease Phenotypes in Zebrafish
Efficient Neuroprotective Rescue of Sacsin-Related Disease Phenotypes in Zebrafish
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Publisher
Basel: MDPI AG
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Language
English
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Publisher
Basel: MDPI AG
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Contents
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a multisystem hereditary ataxia associated with mutations in SACS, which encodes sacsin, a protein of still only partially understood function. Although mouse models of ARSACS mimic largely the disease progression seen in humans, their use in the validation of effective therapies...
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Full title
Efficient Neuroprotective Rescue of Sacsin-Related Disease Phenotypes in Zebrafish
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8395086
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8395086
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms22168401
