Degradation of lipid droplets by chimeric autophagy-tethering compounds
Degradation of lipid droplets by chimeric autophagy-tethering compounds
About this item
Full title
Author / Creator
Fu, Yuhua , Chen, Ningxie , Wang, Ziying , Luo, Shouqing , Ding, Yu and Lu, Boxun
Publisher
Singapore: Springer Singapore
Journal title
Language
English
Formats
Publication information
Publisher
Singapore: Springer Singapore
Subjects
More information
Scope and Contents
Contents
Degrading pathogenic proteins by degrader technologies such as PROTACs (proteolysis-targeting chimeras) provides promising therapeutic strategies, but selective degradation of non-protein pathogenic biomolecules has been challenging. Here, we demonstrate a novel strategy to degrade non-protein biomolecules by autophagy-tethering compounds (ATTECs),...
Alternative Titles
Full title
Degradation of lipid droplets by chimeric autophagy-tethering compounds
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8410765
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8410765
Other Identifiers
ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/s41422-021-00532-7
