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Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation

Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8419052

Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation

About this item

Full title

Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation

Publisher

Australia: Ivyspring International Publisher Pty Ltd

Journal title

Theranostics, 2021-01, Vol.11 (18), p.8964-8976

Language

English

Formats

Publication information

Publisher

Australia: Ivyspring International Publisher Pty Ltd

More information

Scope and Contents

Contents

Modulation of the innate immune system is emerging as a promising therapeutic strategy against Alzheimer's disease (AD). However, determinants of a beneficial therapeutic effect are ill-understood. Thus, we investigated the potential of 18 kDa translocator protein positron-emission-tomography (TSPO-PET) for assessment of microglial activation in mo...

Alternative Titles

Full title

Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8419052

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8419052

Other Identifiers

ISSN

1838-7640

E-ISSN

1838-7640

DOI

10.7150/thno.64022

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