Tepotinib in Non–Small-Cell Lung Cancer with MET Exon 14 Skipping Mutations
Tepotinib in Non–Small-Cell Lung Cancer with MET Exon 14 Skipping Mutations
About this item
Full title
Author / Creator
Paik, Paul K , Felip, Enriqueta , Veillon, Remi , Sakai, Hiroshi , Cortot, Alexis B , Garassino, Marina C , Mazieres, Julien , Viteri, Santiago , Senellart, Helene , Van Meerbeeck, Jan , Raskin, Jo , Reinmuth, Niels , Conte, Pierfranco , Kowalski, Dariusz , Cho, Byoung Chul , Patel, Jyoti D , Horn, Leora , Griesinger, Frank , Han, Ji-Youn , Kim, Young-Chul , Chang, Gee-Chen , Tsai, Chen-Liang , Yang, James C.-H , Chen, Yuh-Min , Smit, Egbert F , van der Wekken, Anthonie J , Kato, Terufumi , Juraeva, Dilafruz , Stroh, Christopher , Bruns, Rolf , Straub, Josef , Johne, Andreas , Scheele, Jürgen , Heymach, John V and Le, Xiuning
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
In a study involving patients with non–small-cell lung cancer with a
MET
exon 14 skipping mutation, the use of tepotinib (a selective MET inhibitor) was associated with a partial response in approximately half the patients. The main adverse event was peripheral edema.
Alternative Titles
Full title
Tepotinib in Non–Small-Cell Lung Cancer with MET Exon 14 Skipping Mutations
Authors, Artists and Contributors
Author / Creator
Felip, Enriqueta
Veillon, Remi
Sakai, Hiroshi
Cortot, Alexis B
Garassino, Marina C
Mazieres, Julien
Viteri, Santiago
Senellart, Helene
Van Meerbeeck, Jan
Raskin, Jo
Reinmuth, Niels
Conte, Pierfranco
Kowalski, Dariusz
Cho, Byoung Chul
Patel, Jyoti D
Horn, Leora
Griesinger, Frank
Han, Ji-Youn
Kim, Young-Chul
Chang, Gee-Chen
Tsai, Chen-Liang
Yang, James C.-H
Chen, Yuh-Min
Smit, Egbert F
van der Wekken, Anthonie J
Kato, Terufumi
Juraeva, Dilafruz
Stroh, Christopher
Bruns, Rolf
Straub, Josef
Johne, Andreas
Scheele, Jürgen
Heymach, John V
Le, Xiuning
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8422679
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8422679
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa2004407
