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The Use, Standardization, and Interpretation of Brain Imaging Data in Clinical Trials of Neurodegene...

The Use, Standardization, and Interpretation of Brain Imaging Data in Clinical Trials of Neurodegene...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8423963

The Use, Standardization, and Interpretation of Brain Imaging Data in Clinical Trials of Neurodegenerative Disorders

About this item

Full title

The Use, Standardization, and Interpretation of Brain Imaging Data in Clinical Trials of Neurodegenerative Disorders

Author / Creator

Publisher

Cham: Springer International Publishing

Journal title

Neurotherapeutics, 2021-04, Vol.18 (2), p.686-708

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Imaging biomarkers play a wide-ranging role in clinical trials for neurological disorders. This includes selecting the appropriate trial participants, establishing target engagement and mechanism-related pharmacodynamic effect, monitoring safety, and providing evidence of disease modification. In the early stages of clinical drug development, evide...

Alternative Titles

Full title

The Use, Standardization, and Interpretation of Brain Imaging Data in Clinical Trials of Neurodegenerative Disorders

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8423963

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8423963

Other Identifiers

ISSN

1933-7213,1878-7479

E-ISSN

1878-7479

DOI

10.1007/s13311-021-01027-4

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