Epo/EpoR signaling in osteoprogenitor cells is essential for bone homeostasis and Epo-induced bone l...
Epo/EpoR signaling in osteoprogenitor cells is essential for bone homeostasis and Epo-induced bone loss
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Publisher
London: Springer Nature B.V
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Language
English
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Publisher
London: Springer Nature B.V
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Contents
High erythropoietin (Epo) levels are detrimental to bone health in adult organisms. Adult mice receiving high doses of Epo lose bone mass due to suppressed bone formation and increased bone resorption. In humans, high serum Epo levels are linked to fractures in elderly men. Our earlier studies indicated that Epo modulates osteoblast activity; howev...
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Full title
Epo/EpoR signaling in osteoprogenitor cells is essential for bone homeostasis and Epo-induced bone loss
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8437981
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8437981
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ISSN
2095-4700
E-ISSN
2095-6231
DOI
10.1038/s41413-021-00157-x
