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Epo/EpoR signaling in osteoprogenitor cells is essential for bone homeostasis and Epo-induced bone l...

Epo/EpoR signaling in osteoprogenitor cells is essential for bone homeostasis and Epo-induced bone l...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8437981

Epo/EpoR signaling in osteoprogenitor cells is essential for bone homeostasis and Epo-induced bone loss

About this item

Full title

Epo/EpoR signaling in osteoprogenitor cells is essential for bone homeostasis and Epo-induced bone loss

Publisher

London: Springer Nature B.V

Journal title

Bone research, 2021-09, Vol.9 (1), p.42-42

Language

English

Formats

Publication information

Publisher

London: Springer Nature B.V

More information

Scope and Contents

Contents

High erythropoietin (Epo) levels are detrimental to bone health in adult organisms. Adult mice receiving high doses of Epo lose bone mass due to suppressed bone formation and increased bone resorption. In humans, high serum Epo levels are linked to fractures in elderly men. Our earlier studies indicated that Epo modulates osteoblast activity; howev...

Alternative Titles

Full title

Epo/EpoR signaling in osteoprogenitor cells is essential for bone homeostasis and Epo-induced bone loss

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8437981

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8437981

Other Identifiers

ISSN

2095-4700

E-ISSN

2095-6231

DOI

10.1038/s41413-021-00157-x

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