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Acute Glucose Shift Induces the Activation of the NLRP3 Inflammasome in THP-1 Cells

Acute Glucose Shift Induces the Activation of the NLRP3 Inflammasome in THP-1 Cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8465199

Acute Glucose Shift Induces the Activation of the NLRP3 Inflammasome in THP-1 Cells

About this item

Full title

Acute Glucose Shift Induces the Activation of the NLRP3 Inflammasome in THP-1 Cells

Publisher

Basel: MDPI AG

Journal title

International journal of molecular sciences, 2021-09, Vol.22 (18), p.9952

Language

English

Formats

Publication information

Publisher

Basel: MDPI AG

More information

Scope and Contents

Contents

We aimed to investigate the effect of acute glucose shift on the activation of the NLRP3 inflammasome, IL-1β secretion, and underlying signaling pathways in THP-1 cells. THP-1 cells were divided into four groups and exposed to the following glucose concentrations for 24 h: constant normal glucose (NG, 5.5 mM), constant high glucose (HG, 25 mM), nor...

Alternative Titles

Full title

Acute Glucose Shift Induces the Activation of the NLRP3 Inflammasome in THP-1 Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8465199

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8465199

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms22189952

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